Minimal residual testing (MRD) testing

  • During or after treatment, this test measures the presence of leukaemia at a molecular level rather than at a cellular level.
  • Biomarkers linked to the leukaemia cells are measured using molecular techniques such as flow cytometry to determine the very small amounts of leukaemia cells which are still remaining in patients.
  • Flow cytometry is a technology used to analyse the physical and chemical characteristics of particles in a fluid as it passes through one or more lasers. A flow cytometer can rapidly measure the size and structures of thousands of cells.
  • MRD provides a very sensitive assessment of remission and an early detection of relapse.