Notice: Function _load_textdomain_just_in_time was called incorrectly. Translation loading for the learndash-course-grid domain was triggered too early. This is usually an indicator for some code in the plugin or theme running too early. Translations should be loaded at the init action or later. Please see Debugging in WordPress for more information. (This message was added in version 6.7.0.) in /home/oquhzfvtvrzo/public_html/wp-includes/functions.php on line 6121

Notice: Function _load_textdomain_just_in_time was called incorrectly. Translation loading for the learndash-paidmemberships domain was triggered too early. This is usually an indicator for some code in the plugin or theme running too early. Translations should be loaded at the init action or later. Please see Debugging in WordPress for more information. (This message was added in version 6.7.0.) in /home/oquhzfvtvrzo/public_html/wp-includes/functions.php on line 6121

Notice: Function _load_textdomain_just_in_time was called incorrectly. Translation loading for the learndash-woocommerce domain was triggered too early. This is usually an indicator for some code in the plugin or theme running too early. Translations should be loaded at the init action or later. Please see Debugging in WordPress for more information. (This message was added in version 6.7.0.) in /home/oquhzfvtvrzo/public_html/wp-includes/functions.php on line 6121

Notice: Function _load_textdomain_just_in_time was called incorrectly. Translation loading for the learndash-zapier domain was triggered too early. This is usually an indicator for some code in the plugin or theme running too early. Translations should be loaded at the init action or later. Please see Debugging in WordPress for more information. (This message was added in version 6.7.0.) in /home/oquhzfvtvrzo/public_html/wp-includes/functions.php on line 6121

Notice: Function _load_textdomain_just_in_time was called incorrectly. Translation loading for the wdm_ld_course_review domain was triggered too early. This is usually an indicator for some code in the plugin or theme running too early. Translations should be loaded at the init action or later. Please see Debugging in WordPress for more information. (This message was added in version 6.7.0.) in /home/oquhzfvtvrzo/public_html/wp-includes/functions.php on line 6121

Notice: Function _load_textdomain_just_in_time was called incorrectly. Translation loading for the learndash domain was triggered too early. This is usually an indicator for some code in the plugin or theme running too early. Translations should be loaded at the init action or later. Please see Debugging in WordPress for more information. (This message was added in version 6.7.0.) in /home/oquhzfvtvrzo/public_html/wp-includes/functions.php on line 6121
Clinical Trials – Leukaemia Care e-learning

Clinical Trials

By Nicole Scully / May 9, 2022

Introduction to Chronic lymphocytic leukaemia (CLL) What is the treatment for CLL? Clinical Trials

CLL treatment has greatly improved due to clinical trials comparing standard treatment with potentially better new treatments.

A Phase 3 trial is currently comparing ibrutinib+obinutuzumab+venetoclax with ibrutinib+obinutuzumab for the treatment of patients with CLL. Clinical trial details are available at https://clinicaltrials.gov/, trial reference: NCT03701282). The study is anticipated to be completed in May 2028.

Tisagenlecleucel (Kymriah^Ò, Novartis Europharm Limited) is the first CAR T‑cell therapy developed to identify leukaemia cells with the CD19 protein. The leukaemia cells once located are then eliminated by the T-cells. Tisagenlecleucel is currently approved in Europe for the treatment of refractory ALL.

The combination of CAR T cells with ibrutinib is currently being investigated for the treatment of CLL. Initial results appears to be promising but further clinical trials are needed.