Use of CVCs in HSCT

For both allogeneic and autologous HSCTs, a tunnelled CVC or port-a-cath is generally inserted to facilitate administration of the following at various stages of the HSCT as required:

  • Conditioning regimen
  • Stem cell infusion
  • IV drugs such as antibiotics
  • Blood products in case of low levels of white blood cells or platelets
  • Fluid supplements to address low levels of electrolytes
  • Any further chemotherapy as required
  • Nutritional support
  • For patients undergoing HSCTs, the minimum waiting time required between insertion of a CVC and the start of the conditioning regimen must be factored into the process.Ā 

Additionally, patientsā€™ continuing education on how to manage the CVC should be undertaken, focusing particularly on preventing complications.

Nursing staff have a central role in the management of CVCs in HSCT patients including:

  • Monitoring of the CVC
  • Prevention of complications
  • Ongoing education of patients on how to manage their CVC, with a focus on avoiding complications
  • Input into determining of the timing for:
  • Scheduling the HSCT
  • Starting the conditioning regimen
  • Optimal length of time for the CVC to remain in placeĀ 
  • Updating the multidisciplinary healthcare team of any side effects.