Understanding blood and its components references

  1. Medvinsky A, Dzierzak E. Definitive hematopoiesis is autonomously initiated by the AGM region. Cell 1996;86:897–906.
  2. Spangrude GJ, Heimfeld S, Weissman IL. Purification and characterization of mouse hematopoietic stem cells. Science 1988;241:58–62.
  3. Kondo M. Lymphoid and myeloid lineage commitment in multipotent hematopoietic progenitors. Immunol Rev 2010;238:37–46.
  4. Adolfsson J, Mansson R, Buza-Vidas N et al. Identification of Flt3+ lympho-myeloid stem cells lacking erythro-megakaryocytic potential: a revised road map for adult blood lineage commitment. Cell 2005;121:295–306.
  5. Busch K, Klapproth K, Barile M et al. Fundamental properties of unperturbed haematopoiesis from stem cells in vivo. Nature 2015;518:542–6.
  6. Baldridge MT, King KY, Boles NC et al. Quiescent haematopoietic stem cells are activated by IFN-gamma in response to chronic infection. Nature2010;465:793–7.
  7. Kondo M, Weissman IL, Akashi K. Identification of clonogenic common lymphoid progenitors in mouse bone marrow. Cell 1997;91:661–72.
  8. Akashi K, Traver D, Miyamoto T, Weissman IL. A clonogenic common myeloid progenitor that gives rise to all myeloid lineages. Nature2000;404:193–7.
  9. Paul F, Arkin Y, Giladi A et al. Transcriptional heterogeneity and lineage commitment in myeloid progenitors. Cell 2015;163:1663–77.
  10. Velten L, Haas SF, Raffel S et al. Human haematopoietic stem cell lineage commitment is a continuous process. Nat Cell Biol 2017;19:271–81.
  11. Essers MA, Offner S, Blanco-Bose WE et al. IFNalpha activates dormant haematopoietic stem cells in vivo. Nature 2009;458:904–8.
  12. Rieger MA, Hoppe PS, Smejkal BM et al. Hematopoietic cytokines can instruct lineage choice. Science 2009;325:217–18.
  13. Lagasse E, Weissman IL. Enforced expression of Bcl-2 in monocytes rescues macrophages and partially reverses osteopetrosis in op/op mice. Cell1997;89:1021–31.
  14. Kondo M, Scherer DC, Miyamoto T et al. Cell-fate conversion of lymphoid-committed progenitors by instructive actions of cytokines. Nature2000;407:383–6.
  15. Kieran MW, Perkins AC, Orkin SH, Zon LI. Thrombopoietin rescues in vitro erythroid colony formation from mouse embryos lacking the erythropoietin receptor. Proc Natl Acad Sci U S A 1996;93:9126–31.
  16. Mercer EM, Lin YC, Murre C. Factors and networks that underpin early hematopoiesis. Semin Immunol 2011;23:317–25.
  17. Persons DA, Allay JA, Allay ER et al. Enforced expression of the GATA-2 transcription factor blocks normal hematopoiesis. Blood 1999;93:488–99.
  18. de Bruijn M, Dzierzak E. Runx transcription factors in the development and function of the definitive hematopoietic system. Blood2017;129:2061–9.
  19. Song WJ, Sullivan MG, Legare RD et al. Haploinsufficiency of CBFA2 causes familial thrombocytopenia with propensity to develop acute myelogenous leukaemia. Nat Genet 1999;23:166–75.
  20. Zhang DE, Zhang P, Wang ND et al. Absence of granulocyte colony-stimulating factor signaling and neutrophil development in CCAAT enhancer binding protein alpha-deficient mice. Proc Natl Acad Sci U S A 1997;94:569–74.
  21. Tawana K, Wang J, Renneville A et al. Disease evolution and outcomes in familial AML with germline CEBPA mutations. Blood 2015;126:1214–23.
  22. Xie H, Ye M, Feng R, Graf T. Stepwise reprogramming of B cells into macrophages. Cell 2004;117:663–76.
  23. Loke J, Chin PS, Keane P et al. C/EBPα overrides epigenetic reprogramming by oncogenic transcription factors in acute myeloid leukemia. Blood Adv 2018;2:271–84. 
  24. Gottgens B. Regulatory network control of blood stem cells. Blood 2015;125:2614–20.
  25. Novershtern N, Subramanian A, Lawton LN et al. Densely interconnected transcriptional circuits control cell states in human hematopoiesis. Cell2011;144:296–309.
  26. Goode DK, Obier N, Vijayabaskar MS etal. Dynamic gene regulatory networks drive hematopoietic specification and differentiation. Dev Cell2016;36:572–87.


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